Adherens Junctions: from Molecular Mechanisms to Tissue by Tony Harris

By Tony Harris

Cell–cell adhesion is prime for the improvement and homeostasis of animal tissues and organs. Adherens junctions (AJs) are the simplest understood cell-cell adhesion complexes. during this quantity, a bunch of the world over famous specialists reports AJ biology over a variety of association; from atoms to molecules, to protein complexes, molecular networks, cells, tissues, and total animal improvement. AJs have additionally been a vital part of animal evolution, and play critical roles in melanoma improvement, pathogen an infection and different ailments. This e-book addresses significant questions encompassing AJ biology.
• How did AJs evolve?
• How do cadherins and catenins have interaction to gather AJs and mediate adhesion?
• How do AJs interface with different mobile equipment to couple adhesion with the complete cellphone?
• How do AJs have an effect on mobile behaviour and multicellular improvement?
• How can irregular AJ job bring about disease?

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